Figure 3. Diagram depicting C. jejuni-virulence determinants and their potential role in the development of C. jejuni-mediated enteritis. The top panel illustrates the interactions of C. jejuni with enterocytes and sites where certain virulence determinants might contribute in disease. The bottom panel illustrates the gross morphological changes that occur in the intestinal tract of an infected host. Not highlighted is the potential interaction of C. jejuni with M cells or professional phagocytic cells, as well as the contribution of the inflammatory response in infection.